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Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron dysfunction disease that leads to paralysis and death. There is currently no established molecular pathogenesis pathway. Multiple proteins involved in RNA processing are linked to ALS, including FUS and TDP43, and we propose a disease...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Proc Natl Acad Sci U S A |
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Κύριοι συγγραφείς: | , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
National Academy of Sciences
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137757/ https://ncbi.nlm.nih.gov/pubmed/27849576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611673113 |
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