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Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells

Rereplication generates double-strand breaks (DSBs) at sites of fork collisions and causes genomic damage, including repeat instability and chromosomal aberrations. However, the primary mechanism used to repair rereplication DSBs varies across different experimental systems. In Drosophila follicle c...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Alexander, Jessica L., Beagan, Kelly, Orr-Weaver, Terry L., McVey, Mitch
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137741/
https://ncbi.nlm.nih.gov/pubmed/27849606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617110113
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