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Mouse model for acute Epstein–Barr virus infection

Epstein–Barr Virus (EBV) infects human B cells and drives them into continuous proliferation. Two key viral factors in this process are the latent membrane proteins LMP1 and LMP2A, which mimic constitutively activated CD40 receptor and B-cell receptor signaling, respectively. EBV-infected B cells el...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Wirtz, Tristan, Weber, Timm, Kracker, Sven, Sommermann, Thomas, Rajewsky, Klaus, Yasuda, Tomoharu
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137732/
https://ncbi.nlm.nih.gov/pubmed/27856754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616574113
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