Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4

Type 2 diabetic (T2D) patients often develop early cognitive and sensorimotor impairments. The pathophysiological mechanisms behind these problems are largely unknown. Recent studies demonstrate that dysfunctional γ-aminobutyric acid (GABAergic) neurons are involved in age-related cognitive decline....

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Larsson, Martin, Lietzau, Grazyna, Nathanson, David, Östenson, Claes-Göran, Mallard, Carina, Johansson, Maria E., Nyström, Thomas, Patrone, Cesare, Darsalia, Vladimer
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137538/
https://ncbi.nlm.nih.gov/pubmed/27780892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160437
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