Exendin-4 Reduces Ischemic Brain Injury in Normal and Aged Type 2 Diabetic Mice and Promotes Microglial M2 Polarization

Exendin-4 is a glucagon-like receptor 1 agonist clinically used against type 2 diabetes that has also shown neuroprotective effects in experimental stroke models. However, while the neuroprotective efficacy of Exendin-4 has been thoroughly investigated if the pharmacological treatment starts before...

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Bibliographische Detailangaben
Hauptverfasser: Darsalia, Vladimer, Hua, Sansan, Larsson, Martin, Mallard, Carina, Nathanson, David, Nyström, Thomas, Sjöholm, Åke, Johansson, Maria E., Patrone, Cesare
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125154/
https://ncbi.nlm.nih.gov/pubmed/25101679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103114
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