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The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride

Type 2 diabetes is a strong risk factor for stroke. Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor in clinical use against type 2 diabetes. The aim of this study was to determine the potential antistroke efficacy of linagliptin in type 2 diabetic mice. To understand whether efficacy was m...

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Detalhes bibliográficos
Main Authors: Darsalia, Vladimer, Ortsäter, Henrik, Olverling, Anna, Darlöf, Emilia, Wolbert, Petra, Nyström, Thomas, Klein, Thomas, Sjöholm, Åke, Patrone, Cesare
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609599/
https://ncbi.nlm.nih.gov/pubmed/23209191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0988
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