Novel anti-EPHA2 antibody, DS-8895a for cancer treatment

Overexpression of EPHA2 has been observed in multiple cancers and reported to be associated with poor prognosis. Here, we produced an afucosylated humanized anti-EPHA2 monoclonal antibody (mAb), DS-8895a for cancer treatment. The antibody recognizes the extracellular juxtamembrane region of EPHA2 an...

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Publicat a:Cancer Biol Ther
Autors principals: Hasegawa, Jun, Sue, Mayumi, Yamato, Michiko, Ichikawa, Junya, Ishida, Saori, Shibutani, Tomoko, Kitamura, Michiko, Wada, Teiji, Agatsuma, Toshinori
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137487/
https://ncbi.nlm.nih.gov/pubmed/27653549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1235663
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