Cargando...

An efficient system for selectively altering genetic information within mRNAs

Site-directed RNA editing (SDRE) is a strategy to precisely alter genetic information within mRNAs. By linking the catalytic domain of the RNA editing enzyme ADAR to an antisense guide RNA, specific adenosines can be converted to inosines, biological mimics for guanosine. Previously, we showed that...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Montiel-González, Maria Fernanda, Vallecillo-Viejo, Isabel C., Rosenthal, Joshua J. C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137428/
https://ncbi.nlm.nih.gov/pubmed/27557710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw738
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!