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Extracellular vesicle-associated Aβ mediates trans-neuronal bioenergetic and Ca(2+)-handling deficits in Alzheimer’s disease models
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder in which aggregation-prone neurotoxic amyloid β-peptide (Aβ) accumulates in the brain. Extracellular vesicles (EVs), including exosomes, are small 50–150 nm membrane vesicles that have recently been implicated in the prion-like sp...
שמור ב:
| הוצא לאור ב: | NPJ Aging Mech Dis |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137253/ https://ncbi.nlm.nih.gov/pubmed/27928512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjamd.2016.19 |
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