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Diverse Neurotoxicants Target the Differentiation of Embryonic Neural Stem Cells into Neuronal and Glial Phenotypes

The large number of compounds that need to be tested for developmental neurotoxicity drives the need to establish in vitro models to evaluate specific neurotoxic endpoints. We used neural stem cells derived from rat neuroepithelium on embryonic day 14 to evaluate the impact of diverse toxicants on t...

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Detalhes bibliográficos
Publicado no:Toxicology
Main Authors: Slotkin, Theodore A., Skavicus, Samantha, Card, Jennifer, Levin, Edward D., Seidler, Frederic J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137195/
https://ncbi.nlm.nih.gov/pubmed/27816694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2016.10.015
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