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Ex Vivo Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma

PURPOSE: Translation of the PDX model into a method for practical personalized cancer treatment is prevented by the intense resources and time necessary to generate and test each tumorgraft. We aimed to develop a high-throughput ex vivo drug testing approach that can be used for personalized cancer...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Roife, David, Dai, Bingbing, Kang, Ya'an, Perez, Mayrim V. Rios, Pratt, Michael, Li, Xinqun, Fleming, Jason B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136340/
https://ncbi.nlm.nih.gov/pubmed/27259561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2936
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