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Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
The physiology of N-Methyl-D-aspartate (NMDA) receptors in mammals is fundamental to brain development and function. NMDA receptors are ionotropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subunits. Activation of NMDA receptors requires binding of neurot...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5136294/ https://ncbi.nlm.nih.gov/pubmed/27135925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17679 |
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