A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy – results from a Swedish cohort study

BACKGROUND: To prevent debilitating and irreversible joint damage, rheumatoid arthritis (RA) is often treated with tumor necrosis factor inhibitor (TNFi), but many patients do not respond to this costly therapy. Few predictors for response are known, and it has been proposed that genetic factors whi...

Full description

Saved in:
Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Jiang, Xia, Askling, Johan, Saevarsdottir, Saedis, Padyukov, Leonid, Alfredsson, Lars, Viatte, Sebastien, Frisell, Thomas
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135751/
https://ncbi.nlm.nih.gov/pubmed/27912794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1174-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items