A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy – results from a Swedish cohort study

BACKGROUND: To prevent debilitating and irreversible joint damage, rheumatoid arthritis (RA) is often treated with tumor necrosis factor inhibitor (TNFi), but many patients do not respond to this costly therapy. Few predictors for response are known, and it has been proposed that genetic factors whi...

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Spremljeno u:
Bibliografski detalji
Izdano u:Arthritis Res Ther
Glavni autori: Jiang, Xia, Askling, Johan, Saevarsdottir, Saedis, Padyukov, Leonid, Alfredsson, Lars, Viatte, Sebastien, Frisell, Thomas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135751/
https://ncbi.nlm.nih.gov/pubmed/27912794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1174-z
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