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Gene-environment interaction between DRB1 shared epitope and smoking regarding risk of ACPA-positive rheumatoid arthritis - all alleles are important
OBJECTIVE: An interaction effect for developing Rheumatoid Arthritis (RA) was previously observed between HLA-DRB1 shared epitope (SE) alleles and smoking. We aimed to further investigate this interaction between distinct SE alleles and smoking regarding risk of developing RA with and without antibo...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732897/ https://ncbi.nlm.nih.gov/pubmed/19479873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24572 |
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