Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease

Mitochondrial movements are tightly controlled to maintain energy homeostasis and prevent oxidative stress. Miro is an outer mitochondrial membrane protein that anchors mitochondria to microtubule motors, and is removed to stop mitochondrial motility as an early step in clearance of dysfunctional mi...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Hsieh, Chung-Han, Shaltouki, Atossa, Gonzalez, Ashley E., da Cruz, Alexandre Bettencourt, Burbulla, Lena F., St Lawrence, Erica, Schüle, Birgitt, Krainc, Dimitri, Palmer, Theo D., Wang, Xinnan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135570/
https://ncbi.nlm.nih.gov/pubmed/27618216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.08.002
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