Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes

Neurons depend on oxidative phosphorylation for energy generation, whereas astrocytes do not, a distinctive feature that is essential for neurotransmission and neuronal survival. However, any link between these metabolic differences and the structural organization of the mitochondrial respiratory ch...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lopez-Fabuel, Irene, Le Douce, Juliette, Logan, Angela, James, Andrew M., Bonvento, Gilles, Murphy, Michael P., Almeida, Angeles, Bolaños, Juan P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135366/
https://ncbi.nlm.nih.gov/pubmed/27799543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613701113
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