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S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3

The lentivirus equine infectious anemia virus (EIAV) encodes the small protein S2, a pathogenic determinant that is important for virus replication and disease progression in horses. No molecular function had been linked to this accessory protein. We report that S2 can replace the activity of Negati...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chande, Ajit, Cuccurullo, Emilia Cristiana, Rosa, Annachiara, Ziglio, Serena, Carpenter, Susan, Pizzato, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135340/
https://ncbi.nlm.nih.gov/pubmed/27803322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612044113
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