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Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy
Duchenne muscular dystrophy (DMD) is an incurable X-linked genetic disease that is caused by a mutation in the dystrophin gene and affects one in every 3,600 boys. We previously showed that long telomeres protect mice from the lethal cardiac disease seen in humans with the same genetic defect, dystr...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135315/ https://ncbi.nlm.nih.gov/pubmed/27799523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615340113 |
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