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IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans
Hepatic fibrosis arises from inflammation in the liver initiated by resident macrophage activation and massive leukocyte accumulation. Hepatic macrophages hold a central position in maintaining homeostasis in the liver and in the pathogenesis of acute and chronic liver injury linked to fibrogenesis....
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Publicado no: | JCI Insight |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135279/ https://ncbi.nlm.nih.gov/pubmed/27942586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88689 |
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