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IFN-ε protects primary macrophages against HIV infection

IFN-ε is a unique type I IFN that is not induced by pattern recognition response elements. IFN-ε is constitutively expressed in mucosal tissues, including the female genital mucosa. Although the direct antiviral activity of IFN-ε was thought to be weak compared with IFN-α, IFN-ε controls Chlamydia m...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Tasker, Carley, Subbian, Selvakumar, Gao, Pan, Couret, Jennifer, Levine, Carly, Ghanny, Saleena, Soteropoulos, Patricia, Zhao, Xilin, Landau, Nathaniel, Lu, Wuyuan, Chang, Theresa L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135270/
https://ncbi.nlm.nih.gov/pubmed/27942584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88255
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