Global Transcriptional Profile of Mycobacterium tuberculosis during THP-1 Human Macrophage Infection

During lung infection, Mycobacterium tuberculosis resides in macrophages and subverts the bactericidal mechanisms of these professional phagocytes. Comprehension of this host-pathogen relationship is fundamental for the development of new therapies to cure and prevent tuberculosis. In this work, we...

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Detalhes bibliográficos
Main Authors: Fontán, Patricia, Aris, Virginie, Ghanny, Saleena, Soteropoulos, Patricia, Smith, Issar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223452/
https://ncbi.nlm.nih.gov/pubmed/18070897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00974-07
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