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SiRNA Targeting mTOR Effectively Prevents the Proliferation and Migration of Human Lens Epithelial Cells

Posterior capsule opacification (PCO) is the most common complication that causes visual decrease after extracapsular cataract surgery. The primary cause of PCO formation is the proliferation of the residual lens epithelial cells (LECs). The mammalian target of rapamycin (mTOR) plays an important ro...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Chunmei, Liu, Jingjing, Jin, Na, Zhang, Guiming, Xi, Yahui, Liu, Hongling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135089/
https://ncbi.nlm.nih.gov/pubmed/27911920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167349
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