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α-Linoleic Acid Enhances the Capacity of α1-Antitrypsin to Inhibit Lipopolysaccharide-Induced IL-1β in Human Blood Neutrophils
Alpha1-antitrypsin (A1AT, SERPINA1), a major circulating inhibitor of neutrophil elastase (NE) and proteinase-3 (PR3), has been proposed to reduce the processing and release of IL-1β. Since the antiinflammatory properties of A1AT are influenced by the presence of polyunsaturated fatty acids, we comp...
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| Publicado no: | Mol Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Feinstein Institute for Medical Research
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135082/ https://ncbi.nlm.nih.gov/pubmed/27452044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00119 |
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