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Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death

Bone morphogenetic proteins (BMPs) are secreted signals that regulate apical ectodermal ridge (AER) functions and interdigital programmed cell death (PCD) of developing limb. However the identities of the intracellular mediators of these signals are unknown. To investigate the role of Smad proteins...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Wong, Yuk Lau, Behringer, Richard R., Kwan, Kin Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134426/
https://ncbi.nlm.nih.gov/pubmed/22240098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.12.037
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