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Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death
Bone morphogenetic proteins (BMPs) are secreted signals that regulate apical ectodermal ridge (AER) functions and interdigital programmed cell death (PCD) of developing limb. However the identities of the intracellular mediators of these signals are unknown. To investigate the role of Smad proteins...
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Publicado no: | Dev Biol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5134426/ https://ncbi.nlm.nih.gov/pubmed/22240098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.12.037 |
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