Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses

Complexin (Cplx) proteins modulate the core SNARE complex to regulate exocytosis. To understand the contributions of Cplx to signaling in a well-characterized neural circuit, we investigated how Cplx3, a retina-specific paralog, shapes transmission at rod bipolar (RB) → AII amacrine cell synapses in...

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Udgivet i:Cell Rep
Main Authors: Mortensen, Lena S., Park, Silvia J.H., Ke, Jiang-bin, Cooper, Benjamin H., Zhang, Lei, Imig, Cordelia, Löwel, Siegrid, Reim, Kerstin, Brose, Nils, Demb, Jonathan B., Rhee, Jeong-Seop, Singer, Joshua H.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134263/
https://ncbi.nlm.nih.gov/pubmed/27239031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.012
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