Autosomal genetic control of human gene expression does not differ across the sexes

BACKGROUND: Despite their nearly identical genomes, males and females differ in risk, incidence, prevalence, severity and age-at-onset of many diseases. Sexual dimorphism is also seen in human autosomal gene expression, and has largely been explored by examining the contribution of genotype-by-sex i...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Kassam, Irfahan, Lloyd-Jones, Luke, Holloway, Alexander, Small, Kerrin S., Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Gibson, Greg, Spector, Tim D., Esko, Tonu, Montgomery, Grant W., Powell, Joseph E., Yang, Jian, Visscher, Peter M., McRae, Allan F.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134098/
https://ncbi.nlm.nih.gov/pubmed/27908293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1111-0
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