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The effect of X-linked dosage compensation on complex trait variation
Quantitative genetics theory predicts that X-chromosome dosage compensation (DC) will have a detectable effect on the amount of genetic and therefore phenotypic trait variances at associated loci in males and females. Here, we systematically examine the role of DC in humans in 20 complex traits in a...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614401/ https://ncbi.nlm.nih.gov/pubmed/31285442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10598-y |
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