ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

Epidemiological evidence from the current outbreak of Zika virus (ZIKV) and recent studies in animal models indicate a strong causal link between ZIKV and microcephaly. ZIKV infection induces cell-cycle arrest and apoptosis in proliferating neural progenitors. However, the mechanisms leading to thes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ghouzzi, Vincent El, Bianchi, Federico T, Molineris, Ivan, Mounce, Bryan C, Berto, Gaia E, Rak, Malgorzata, Lebon, Sophie, Aubry, Laetitia, Tocco, Chiara, Gai, Marta, Chiotto, Alessandra MA, Sgrò, Francesco, Pallavicini, Gianmarco, Simon-Loriere, Etienne, Passemard, Sandrine, Vignuzzi, Marco, Gressens, Pierre, Di Cunto, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133962/
https://ncbi.nlm.nih.gov/pubmed/27787521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.266
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados