The Role of Deoxycytidine Kinase (dCK) in Radiation-Induced Cell Death

Deoxycytidine kinase (dCK) is a key enzyme in deoxyribonucleoside salvage and the anti-tumor activity for many nucleoside analogs. dCK is activated in response to ionizing radiation (IR)-induced DNA damage and it is phosphorylated on Serine 74 by the Ataxia-Telangiectasia Mutated (ATM) kinase in ord...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Zhong, Rui, Xin, Rui, Chen, Zongyan, Liang, Nan, Liu, Yang, Ma, Shumei, Liu, Xiaodong
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133934/
https://ncbi.nlm.nih.gov/pubmed/27879648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111939
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