Modulation of deoxycytidine kinase (dCK) and glycogen synthase kinase (GSK-3β) by anti-CD20 (rituximab) and 2-chlorodeoxyadenosine (2-CdA) in human lymphoid malignancies

BACKGROUND: The combination of rituximab and 2-CdA is an effective therapy for B-cell tumors. However, the molecular mechanisms and enzymatic pathways involved in the interaction between the two agents are not fully understood. In this study, we provide molecular evidence for positive interaction be...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Al-Katib, Ayad M, Aboukameel, Amro, Ebrahim, AbdulShukkur, Beck, Frances WJ, Tekyi-Mensah, Samuel E, Raufi, Ali, Ahmed, Yasin, Mandziara, Mary, Kafri, Zyad
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417330/
https://ncbi.nlm.nih.gov/pubmed/25937997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-31
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados