Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor 1 (BIG1) Governs the Recruitment of Tumor Necrosis Factor Receptor-Associated Factor 2 (TRAF2) to Tumor Necrosis Factor Receptor 1 (TNFR1) Signaling Complexes

Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a critical mediator of tumor necrosis factor-α (TNF-α) signaling. However, the regulatory mechanisms of TRAF2 are not fully understood. Here we show evidence that TRAF2 requires brefeldin A-inhibited guanine nucleotide-exchange factor 1 (...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Noguchi, Takuya, Tsuchida, Mei, Kogue, Yosuke, Spadini, Christian, Hirata, Yusuke, Matsuzawa, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133869/
https://ncbi.nlm.nih.gov/pubmed/27834853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111869
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