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5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients
Glioblastomas exhibit widespread molecular alterations including a highly distorted epigenome. Here, we resolve genome-wide 5-methylcytosine and 5-hydroxymethylcytosine in glioblastoma through parallel processing of DNA with bisulfite and oxidative bisulfite treatments. We apply a statistical algori...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133638/ https://ncbi.nlm.nih.gov/pubmed/27886174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13177 |
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