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Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models

To understand the persistence of latently HIV-1 infected cells in virally suppressed infected patients, a number of in vitro models of HIV latency have been developed. In an attempt to mimic the in vivo situation as closely as possible, several models use primary cells and replication-competent viru...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bonczkowski, Pawel, De Scheerder, Marie-Angélique, Malatinkova, Eva, Borch, Alexandra, Melkova, Zora, Koenig, Renate, De Spiegelaere, Ward, Vandekerckhove, Linos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133580/
https://ncbi.nlm.nih.gov/pubmed/27910923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38329
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