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Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis

N-acyl-homoserine lactones (AHLs) are small diffusible molecules called autoinducers that mediate cell-to-cell communications. Enzymatic degradation of AHLs is a promising bio-control strategy known as quorum-quenching. To improve the quorum-quenching activity of a thermostable esterase Est816, whic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Xiwen, Cao, Li-chuang, Fan, Xin-jiong, Liu, Yu-huan, Xie, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133562/
https://ncbi.nlm.nih.gov/pubmed/27909291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38137
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