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Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements

Dynamic redefinition of the 10 UGAs in human and mouse selenoprotein P (Sepp1) mRNAs to specify selenocysteine instead of termination involves two 3′ UTR structural elements (SECIS) and is regulated by selenium availability. In addition to the previously known human Sepp1 mRNA poly(A) addition site...

詳細記述

保存先:
書誌詳細
出版年:Open Biol
主要な著者: Wu, Sen, Mariotti, Marco, Santesmasses, Didac, Hill, Kristina E., Baclaocos, Janinah, Aparicio-Prat, Estel, Li, Shuping, Mackrill, John, Wu, Yuanyuan, Howard, Michael T., Capecchi, Mario, Guigó, Roderic, Burk, Raymond F., Atkins, John F.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133445/
https://ncbi.nlm.nih.gov/pubmed/27881738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160241
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