Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements

Dynamic redefinition of the 10 UGAs in human and mouse selenoprotein P (Sepp1) mRNAs to specify selenocysteine instead of termination involves two 3′ UTR structural elements (SECIS) and is regulated by selenium availability. In addition to the previously known human Sepp1 mRNA poly(A) addition site...

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Опубликовано в: :Open Biol
Главные авторы: Wu, Sen, Mariotti, Marco, Santesmasses, Didac, Hill, Kristina E., Baclaocos, Janinah, Aparicio-Prat, Estel, Li, Shuping, Mackrill, John, Wu, Yuanyuan, Howard, Michael T., Capecchi, Mario, Guigó, Roderic, Burk, Raymond F., Atkins, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133445/
https://ncbi.nlm.nih.gov/pubmed/27881738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160241
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