Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

Ames dwarf mice (Prop1(df/df)) are long-lived due to a loss of function mutation, resulting in deficiency of GH, TSH, and prolactin. Along with a marked extension of longevity, Ames dwarf mice have improved energy metabolism as measured by an increase in their oxygen consumption and heat production,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Endocrinology
Prif Awduron: Darcy, Justin, McFadden, Samuel, Fang, Yimin, Huber, Joshua A., Zhang, Chi, Sun, Liou Y., Bartke, Andrzej
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133358/
https://ncbi.nlm.nih.gov/pubmed/27740871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1593
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