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Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats

Specialized metabolic sensors in the hypothalamus regulate blood glucose levels by influencing hepatic glucose output and hypoglycemic counterregulatory responses. Hypothalamic reactive oxygen species (ROS) may act as a metabolic signal-mediating responses to changes in glucose, other substrates and...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Pauliina Markkula, S., Lyons, David, Yueh, Chen-Yu, Riches, Christine, Hurst, Paul, Fielding, Barbara, Heisler, Lora K., Evans, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133351/
https://ncbi.nlm.nih.gov/pubmed/27740870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2054
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