Brain Glucose Sensors Play a Significant Role in the Regulation of Pancreatic Glucose-Stimulated Insulin Secretion

As patients decline from health to type 2 diabetes, glucose-stimulated insulin secretion (GSIS) typically becomes impaired. Although GSIS is driven predominantly by direct sensing of a rise in blood glucose by pancreatic β-cells, there is growing evidence that hypothalamic neurons control other aspe...

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Bibliographic Details
Main Authors: Osundiji, Mayowa A., Lam, Daniel D., Shaw, Jill, Yueh, Chen-Yu, Markkula, S. Pauliina, Hurst, Paul, Colliva, Carolina, Roda, Aldo, Heisler, Lora K., Evans, Mark L.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266403/
https://ncbi.nlm.nih.gov/pubmed/22210318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1050
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