Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats

Circadian disruption and obesity synergize to predispose to development of type 2 diabetes mellitus (T2DM), signifying that therapeutic targeting of both circadian and metabolic dysfunctions should be considered as a potential treatment approach. To address this hypothesis, we studied rats concomita...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Thomas, Anthony P., Hoang, Jonathan, Vongbunyong, Kenny, Nguyen, Andrew, Rakshit, Kuntol, Matveyenko, Aleksey V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133345/
https://ncbi.nlm.nih.gov/pubmed/27653034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1309
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