Prostatic Acid Phosphatase Alters the RANKL/OPG System and Induces Osteoblastic Prostate Cancer Bone Metastases

Prostate cancer (PCa) is unique in its tendency to produce osteoblastic (OB) bone metastases. There are no existing therapies that specifically target the OB phase that affects 90% of men with bone metastatic disease. Prostatic acid phosphatase (PAP) is secreted by PCa cells in OB metastases and inc...

詳細記述

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書誌詳細
出版年:Endocrinology
主要な著者: Kirschenbaum, Alexander, Izadmehr, Sudeh, Yao, Shen, O'Connor-Chapman, Kieley L., Huang, Alan, Gregoriades, Elias M., Yakar, Shoshana, Levine, Alice C.
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2016
主題:
Rapid Communication
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133341/
https://ncbi.nlm.nih.gov/pubmed/27783536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1606
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