Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity

Regulation of gene expression in immune cells is known to be under genetic control, and likely contributes to susceptibility to autoimmune diseases, such as multiple sclerosis (MS). How this occurs in concert across multiple immune cell types is poorly understood. Using a mouse model that harnesses...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Bearoff, Frank, del Rio, Roxana, Case, Laure K., Dragon, Julie A., Nguyen-Vu, Trang, Lin, Chin-Yo, Blankenhorn, Elizabeth P., Teuscher, Cory, Krementsov, Dimitry N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133152/
https://ncbi.nlm.nih.gov/pubmed/27653816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.37
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