The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease

Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases. Here, using chromosome Y (ChrY) consomic mouse strains on the C57BL/6J (B6) background, we show that susceptibility to two diverse animal model...

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Detalhes bibliográficos
Main Authors: Case, Laure K., Wall, Emma H., Dragon, Julie A., Saligrama, Naresha, Krementsov, Dimitry N., Moussawi, Mohamad, Zachary, James F., Huber, Sally A., Blankenhorn, Elizabeth P., Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759723/
https://ncbi.nlm.nih.gov/pubmed/23800453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.156703.113
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