Effects of Two-Year Vitamin B(12) and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT

Lowering elevated plasma homocysteine (Hcy) concentrations by supplementing vitamin B(12) and folic acid may reduce depressive symptoms and improve health-related quality of life (HR-QoL) in older adults. This study aimed to test this hypothesis in a randomized controlled trial. Participants (N = 29...

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Publicado no:Nutrients
Main Authors: de Koning, Elisa J., van der Zwaluw, Nikita L., van Wijngaarden, Janneke P., Sohl, Evelien, Brouwer-Brolsma, Elske M., van Marwijk, Harm W. J., Enneman, Anke W., Swart, Karin M. A., van Dijk, Suzanne C., Ham, Annelies C., van der Velde, Nathalie, Uitterlinden, André G., Penninx, Brenda W. J. H., Elders, Petra J. M., Lips, Paul, Dhonukshe-Rutten, Rosalie A. M., van Schoor, Natasja M., de Groot, Lisette C. P. G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133130/
https://ncbi.nlm.nih.gov/pubmed/27886078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu8110748
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