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Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice
Previous studies provided evidence for the alteration of brain cholesterol homeostasis in 129.Mecp2-null mice, an experimental model of Rett syndrome. The efficacy of statins in improving motor symptoms and prolonging survival of mutant mice suggested a potential role of statins in the therapy of Re...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5132339/ https://ncbi.nlm.nih.gov/pubmed/27892851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22409 |
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