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Ambroxol effects in glucocerebrosidase and α‐synuclein transgenic mice
OBJECTIVE: Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase. Both homozygous and heterozygous glucocerebrosidase 1 mutations confer an increased risk for developing Parkinson disease. Current estimates indica...
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| Опубликовано в: : | Ann Neurol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5132106/ https://ncbi.nlm.nih.gov/pubmed/27859541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24790 |
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