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TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study

BACKGROUND AND AIM: TP53 encodes p53, which has a crucial role in modulating genes that regulate defense against cancer development. This study investigated whether TP53 polymorphisms are associated with colorectal cancer (CRC) in patients with Lynch syndrome and whether TP53 interacts with lifestyl...

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Pubblicato in:PLoS One
Autori principali: Kamiza, Abram Bunya, Hsieh, Ling-Ling, Tang, Reiping, Chien, Huei-Tzu, Lai, Chih-Hsiung, Chiu, Li-Ling, Lo, Tsai-Ping, Hung, Kuan-Yi, You, Jeng-Fu, Wang, Wen-Chang, Hsiung, Chao A., Yeh, Chih-Ching
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131981/
https://ncbi.nlm.nih.gov/pubmed/27907203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167354
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