Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio

BACKGROUND: The hyperglycemic clamp test, the gold standard of beta cell function, predicts impending type 1 diabetes in islet autoantibody-positive individuals, but the latter may benefit from less invasive function tests such as the proinsulin:C-peptide ratio (PI:C). The present study aims to opti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Van Dalem, Annelien, Demeester, Simke, Balti, Eric V., Keymeulen, Bart, Gillard, Pieter, Lapauw, Bruno, De Block, Christophe, Abrams, Pascale, Weber, Eric, Vermeulen, Ilse, De Pauw, Pieter, Pipeleers, Daniël, Weets, Ilse, Gorus, Frans K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131964/
https://ncbi.nlm.nih.gov/pubmed/27907006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166702
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