Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio

BACKGROUND: The hyperglycemic clamp test, the gold standard of beta cell function, predicts impending type 1 diabetes in islet autoantibody-positive individuals, but the latter may benefit from less invasive function tests such as the proinsulin:C-peptide ratio (PI:C). The present study aims to opti...

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Udgivet i:PLoS One
Main Authors: Van Dalem, Annelien, Demeester, Simke, Balti, Eric V., Keymeulen, Bart, Gillard, Pieter, Lapauw, Bruno, De Block, Christophe, Abrams, Pascale, Weber, Eric, Vermeulen, Ilse, De Pauw, Pieter, Pipeleers, Daniël, Weets, Ilse, Gorus, Frans K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131964/
https://ncbi.nlm.nih.gov/pubmed/27907006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166702
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