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NRF2: Translating the Redox Code

Cancer requires mechanisms to mitigate reactive oxygen species (ROS) generated during rapid growth, such as induction of the antioxidant transcription factor, Nrf2. However, the targets of ROS-mediated cytotoxicity are unclear. Recent studies in pancreatic cancer show that redox control by Nrf2 prev...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Tummala, Krishna S., Kottakis, Filippos, Bardeesy, Nabeel
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131791/
https://ncbi.nlm.nih.gov/pubmed/27555347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2016.08.002
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