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NRF2: Translating the Redox Code

Cancer requires mechanisms to mitigate reactive oxygen species (ROS) generated during rapid growth, such as induction of the antioxidant transcription factor, Nrf2. However, the targets of ROS-mediated cytotoxicity are unclear. Recent studies in pancreatic cancer show that redox control by Nrf2 prev...

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Bibliografiske detaljer
Udgivet i:Trends Mol Med
Main Authors: Tummala, Krishna S., Kottakis, Filippos, Bardeesy, Nabeel
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131791/
https://ncbi.nlm.nih.gov/pubmed/27555347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2016.08.002
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